Brucella Canis
Frequently Asked Questions about Brucella canis (B. canis)
What is Brucella canis?
Brucella canis is a bacteria that causes an illness called brucellosis. It primarily infects dogs, but has been documented to cause illness in humans and very rarely other wild canids (cat and dog type animals) . There are other types of Brucella bacteria (B. ovis, B, abortus, B. melitensis) that can cause a variety of other diseases which are all generally referred to as brucellosis.
How do dogs get Brucella canis?
Infected animals shed the bacteria in aborted materials (placenta / fetuses), vaginal discharge, semen, and seminal fluid. However, the Brucella bacteria can be shed throughout the life of an infected dog in their urine, blood, saliva, and more rarely in feces, nose, and eye secretions. Transmission usually occurs during breeding, whelping / abortion, and estrus via the mouth, nose, eyes, broken skin or in utero or nursing in puppies.
What are the signs of Brucella canis in dogs?
Typically the only signs in dogs are reproductive:
- Abortion (3rd trimester) / stillbirth / poor doers
- Infertility
- Vaginal discharge (can last weeks)
Rarely the following signs can be exhibited:
- Scrotal swelling, edema, pain, and self mutilation
- Swelling of the internal male reproductive organs which can lead to difficulty urinating and defecating
- Lymph node swelling
- Testicle shrinkage and abnormal sperm
- Lethargy, fatigue, and exercise intolerance
- Inappetence and weight loss
- Lameness and pain from back bone infection
- Eye pain and internal inflammation
How is Brucella canis diagnosed in animals?
This disease is very difficult to diagnose. Often all other tests will come back normal. The best diagnosis is to submit aborted placenta, tissue, and fluids to the lab to grow the bacteria. Blood tests can be used to determine if an animal has been infected with bacteria previously, but can take up to 4 months after infection to show up positive.
Unfortunately, animals shed the bacteria intermittently, so all breeding dogs should be tested a few weeks before any breeding activity.
How do you prevent B. canis in your kennel?
- Test all dogs (male and female) and remove any positives.
- For all new additions, isolate and test upon arrival and 1 month later before allowing them into your shared kennel spaces.
- If the above measures are not followed, test all dogs a few weeks before each breeding.
- Practice strict monitoring. biosecurity and disease.
- Clean and disinfect on a daily basis, especially whelping and nursery sites.
- Isolate all whelping females and maintain this separation if any signs of disease are noted.
Can people get Brucella canis?
Yes. Although the risk is low, humans exposed to whelping / aborting dogs should wear protective gloves and clothing. Interacting with infected dogs at other times is considered very low risk, but transmission is not impossible. People who are immunocompromised are at increased risk from severe infection.
What are the symptoms of B. canis in people?
- Extremely variable and often not specific:
- Fever (periodic and at night)
- Fatigue and weakness
- Chills and sweats
- Headaches
- Weight loss
In some cases, the disease can become severe and cause infection and problems in the joints, heart, spine, lungs, mouth, spleen, liver, and brain.
How can breeders protect themselves?
Wear gloves any time you are assisting with whelping, especially in the case of stillbirths and abortions. Use masks and goggles when cleaning and disinfecting infected or isolation areas.
What do I do if I suspect that I or one of my workers has brucellosis?
Anyone showing symptoms of brucellosis should see a doctor. Visit ualhd.org to find your local health department for more information.
Prevention and Control
About the Bacteria
Brucella canis is a bacteria that is easy to kill on hard surfaces, but can last months inside organic material (feces and dirt).
The bacteria can be spread through the air when the environment is cool, dark and has a high humidity. B. canis lives within biofilms (thin, slimy mats of bacteria that stick to surfaces) and can be moved around on tools, clothes, and even your hands. Keeping your kennel areas warm, dry, and allowing sun exposure can help decrease the amount of B. canis bacteria living in the environment.
How B. Canis spreads
Most common:
- Vaginal discharge around the time of an abortion, whelping, or heat
- Semen or urine from positive males
Less common:
- Female urine
- Feces, saliva, blood, and milk
Rigid Biosecurity
Routine Cleaning and Disinfection
- Remove solid waste
- Clean with a degreaser and rinse 2
- Make sure to scrub to disrupt and remove biofilms
- Disinfect
- Make sure all surfaces have at least 10 minutes of contact time
- Completely rinse off disinfectant
- Allow surfaces to fully dry
- Expose to sunlight, if possible
Order of operations
- Conduct all husbandry activities from youngest to oldest, least to most exposed
- Change shoes and clothes and wash hands between groups of dogs
Personal Protection
- One time use or washable gloves, goggles, masks, boots and clothing protective layers
- Thorough hand washing
- Consult with Public Health or your doctor for more specific recommendations
Education
- Teach anyone entering the animal areas of the property how to stay protected
- Limit interactions between dogs
- Limit interactions between dogs and people
Effective Disinfectants
- 25% sodium hypochlorite (bleach)
- Quarternary ammonium 70% ethanol
Maintaining a Free Kennel
Testing Free
New Dog Introductions
- Test immediately upon arrival
- Strictly quarantine away from all other dogs
- Retest after 8-12 weeks of strict isolation
- Only allow to interact with your other dogs after both tests return negative
Breeding Animals
- Use artificial insemination, if possible
- Test males within 3 weeks prior to breeding
- If you must use live cover
- Test both male and female within 3 weeks prior to breeding
- Test all dogs bred by outside animals every 3-6 months
Husbandry
Maintain a closed facility
- All dogs entering must undergo the new dog isolation and testing
- Any dog who leaves (other than for a scheduled c-section) must follow the same isolation and testing to reenter
Make an isolation area
- Completely separate from other dog areas
- Feed, clean, and exercise these animals last
- Change clothes and shoes, wash hands or wear gloves
Cleaning and Disinfection (3 step process)
- Remove solids
- Clean with a degreaser and scrub to remove and prevent biofilm formation
- Disinfect
Biosecurity
- Restrict human, animal and pest access to your facility
- Anyone who has had contact with outside dogs must:
- Wash their hands
- Change their clothes and shoes
Testing for Brucella Canis
Testing is complex, please contact the Utah State Veterinarianโs Office for planning assistance.
Testing
New Dog Entry Testing
- Any dog entering your facility
- Test immediately upon arrival
- Strictly quarantine away from all other dogs
- Retest after 8-12 weeks of strict isolation
- Only allow to interact with your other dogs after both tests return negative
Whole Kennel
- Every 12 months:
- Test every dog over 6 weeks old
- Best when females are close to or in heat
- Delay testing on dogs who have received an antibiotic within the last 3 months
Breeding Animals
- When using artificial insemination: Test males within 3 weeks prior to breeding
- If using live cover: Test males and female within 3 weeks prior to breeding
Test Interpretation
Positive Result
- Both screening and confirmatory test positive
- See B. canis Positive Dog Guidance
Suspicious Result
- Screening test positive
- Confirmatory test negative
- Retest every 4 weeks
Test Types
Screening Tests
- IFA
- AGID(cwa)
Confirmatory Tests
- Multiplex
- Blood or Urine Culture
- 3 tests
- Collected at least 24 hours apart
Testing Laboratories
- Utah State University Utah Veterinary Diagnostic Lab (IFA - screening test): 950 E 1400 N, Logan, UT 84341 (435) 797-1895
- Cornell University Animal Health Diagnostic Center (AGID (cwa) / Multiplex / Cultures): 240 Farrier Rd, Ithaca, NY 14853, (607) 253-3900
Positive Dog Guidance
The tough decision
There is no effective treatment for dogs infected with B. canis. Often these animals will initially look perfectly healthy, but over time they may develop infections in their spine, eyes and other organs. Some animals may clear the infection after 2-5 years, but there is no guarantee and it is very difficult to determine if a dog is free of the disease.
Regardless of how healthy they look, B. canis infected dogs will shed the bacteria on and off. Most is shed in vaginal discharge during whelping, abortion and heats, and in the semen and urine of male dogs. Unfortunately, even spayed and neutered dogs may shed the bacteria in their feces, urine, saliva, milk and blood.
Because infected dogs are a danger to other dogs and people, it is strongly recommended that these animals be euthanized. This is a heartbreaking decision, that should be made in consultation with your veterinarian and the Utah State Veterinarianโs Office.
Risk to people
B. canis can causes infection in people. Follow the steps below to keep you and your family safe around dogs carrying the disease.
Living with a positive dog
Sterilization
- It is STRONGLY RECOMMENDED that infected dogs are immediately spayed / neutered
Lifetime Isolation
- Your positive dog can never have contact with any other dogs
- They must be kept on your property at all times with no outside visitors
Personal Protection
See Brucella canis: Prevention and Control
Treatment
- The decision to treat is dependent on your veterinarian
- Treatment may be months to years long, expensive, and in most cases does not result in a cure
Declaration
- You must let us know what you decide to do with your positive dog
- You must notify anyone who may come in contact with your dog that they are positive, especially veterinarians, their staff and visitors to your home